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    • Dr. Meetu Gupta

    Associate Professor

    Office Address:
    Department of Biotechnology,
    Jamia Millia Islamia (Central University),
    New Delhi 110025

    Education, Training & Experience

    • Associate Professor, Department of Biotechnology (2017-Present).
    • Assistant Professor, Department of Biotechnology (2007-2017).
    • CSIR Pool Officer, School of Life Sciences, Jawaharlal Nehru University, New Delhi (2005 – 2007).
    • Principal Investigator, DST Young Scientist, School of Life Sciences, Jawaharlal Nehru University, New Delhi (2002- 2005).
    • Guest Researcher, Dept. of Pharmaceutical Biology, University of Wuerzburg, Germany (April 2002 - June 2002).
    • CSIR Research Associate, National Botanical Research Institute, Lucknow (1997- 2002).
    • CSIR-SRF, National Botanical Research Institute, Lucknow (1996-1997).
    • Ph.D. in Botany, National Botanical Research Institute, Lucknow (1992-1996).
    • Master of Science (M.Sc.) Botany, Banaras Hindu University, Varanasi (1991).                               

    Lab Members : Ph.D. Guidance

    Medha Panthri (Project Assistant)

    Ph.D. Scholar:(2016-Present)

    Email- medhapanthri@gmail.com

    Zainab Mirza (UGC-Fellow)

    Ph.D. Scholar: (2017-Present)

    Email- zainabmirza831@gmail.com  



    Himanshu Saini (UGC-Fellow)

    Ph.D. Scholar: (2019-Present)

    Email- himanshu20saini@gmail.com

    Priyanka Bhatia (UGC-Fellow)

    Ph.D. Scholar: 2019-Present

    Email- priyankabhatia1095@gmail.com

    Narjis Saba Khatoon (CSIR-JRF)

    Ph.D. Scholar: 2019-Present

    Email- narjissaba5@gmail.com

    Asna Khan (CSIR-JRF)

    Ph.D. Scholar: 2019-Present

    Email- asnakhan604@gmail.com

    Photo Gallery: Ecotoxicogenomics Research Laboratory

    Research Overview

    Our group is interested in understanding the metal transport and its regulation through physiological, biochemical and molecular mechanisms.  Plants develop different mechanisms to cope up with different metal toxicity throughout their life span. Arsenic (As) is classified as a metalloid having properties of both metals and non-metals; which can take part in a wide range of chemical interactions. Bioavailability, uptake and phyto-toxicity of As to plants are influenced by various factors such as As concentration in soil/water, As species, plants species and soil/water properties. As-contaminated ground water irrigation is one of the major factors that affect all organisms live in term of health and food safety. Rice and Indian mustard are two plants we are using to identify the behavior of As in plant system. Our main focus is to deal with the following topics:

    1. Interaction of As with other metals, having similar chemical properties, and share same transport system, mainly in rice and mustard plant
    2. Cellular/molecular mechanisms involved in As stressed plants under submerged and drought condition.
    3. How auxin redistribution and nitrogen signalling pathways regulates root architecture under As stress.
    4. Identification and utilization of genes and miRNA for development of As tolerant plants.
    5. Identification of interacting partners of pre-identified transporters during arsenic-iron coupling in rice varieties using protein-protein interaction assays.

    Research Projects

    1. From University Grant Commission, India for a period of three years from 2009-2012 entitled “Molecular Characterization of Arsenic Induced Markers in Indian Mustard and Rice”

      Total Cost: Rs. 11,40,000

    2. From Ministry of Environment and Forest (MoEF), Govt. of India for a period of three and a half years from 2009-2013 entitled “Cellular/Molecular Mechanism Involved For Arsenic Detoxification and Tolerance in Rice and Indian Mustard Varieties

      Total Cost:  Rs. 27,00,000

    3. From SERB-DST for a period of three years 2018- Present entitled “Nutrient and Metabolite Profiling of Rice and Wheat Genotypes in Arsenic Contaminated Areas of Ballia District (U.P)

      Total Cost: Rs. 34,54,000

    Research Publications, Reviews & Book Chapters

    1. Medha Panthri and Meetu Gupta (2019) Facets of iron in arsenic exposed Oryza sativa varieties: A manifestation of plant’s adjustment at morpho-biochemical and enzymatic levels. Environmental Pollution, 255, 113289. [IF: 8.07]
    2. Afsana Praveen, Ashutosh Pandey and Meetu Gupta (2019) Nitric oxide alters nitrogen metabolism and PIN gene expressions by playing protective role in arsenic challenged Brassica juncea L. ‘Ecotoxicology and Environmental Safety, 176, 95-107. [IF: 6.92]
    3. Afsana Praveen and Meetu Gupta (2018) Nitric oxide confronts arsenic stimulated oxidative stress and root architecture through distinct gene expression of auxin transporters, nutrient related genes and modulates biochemical responses in Oryza sativa L. “Environmental Pollution” , 240, 950-962. [IF: 8.07]
    4. Chandana Pandey and Meetu Gupta (2015) Selenium and auxin mitigates arsenic stress in rice (Oryza sativa L.) by combining the role of stress indicators, modulators and genotoxicity assay. J. Hazard. Mat.287, 384-391. [IF: 10.5]
    5. Meetu Gupta and Mohd. Anwar Ahmad (2014) Arsenate induced differential response in rice genotypes. Ecotoxicology and Environmental Safety. 107, 46-54. [IF: 6.92]  
    6. Mohd. Anwar Ahmad, Rashmi Gaur and Meetu Gupta (2012) Comparative biochemical and RAPD analysis in two varieties of rice (Oryza sativa) under arsenic stress by using various biomarkers. J. Hazard. Mat.  217-218, 141-148. [IF: 10.5]
    7. Gupta M., Sharma P., Sarin N.B. & Sinha A.K. (2009) Differential response of arsenic stress in two varieties of Brassica juncea L. Chemosphere (74): 1201-1208. [IF: 7.08]

     

    (Journals Impact factor 4-6, as corresponding author)

    1. Seema Sahay, L Robledo-Arratia, K Glowacka, Meetu Gupta (2021) Root NRT, NiR,AMT, GS, GOGAT and GDH expression level reveal NO and ABA mediated drought tolerance in Brassica juncea L.Scientific Reports 11 (1), 1-15. [IF: 4.37]
    2. Seema Sahay,  Ehasanullah Khan,  Afsana Praveen,  Medha Panthri, Zainab Mirza and Meetu Gupta (2020) Sulphur potentiates selenium to alleviate arsenic-induced stress by modulating oxidative stress, accumulation and thiol-ascorbate metabolism in  Brassica juncea L. Environmental Science and Pollution Research, 27 (11), 11697-11713. [IF: 4.01]
    3. Seema Sahay,  Ehasanullah Khan and Meetu Gupta (2019)  Nitric oxide and abscisic acid protects against PEG-induced drought stress differentially in Brassica genotypes by combining the role of stress modulators, markers and antioxidants. Nitric Oxide, 89, 81-92. [IF: 4.36]
    4. Ehasanullah Khan and Meetu Gupta (2018) Arsenic–silicon priming of rice (Oryza sativa L.) seeds influence mineral nutrient uptake and biochemical responses through modulation of Lsi-1, Lsi-2, Lsi-6 and nutrient transporter genes.  “Scientific Report”, 8 (1), 1-16. [IF: 4.37]
    5. Afsana Praveen, Ehasanullah Khan, Serena Ngiimei D, Mohammad Perwez, Meryam Sardar and Meetu Gupta  (2018) Iron oxide nanoparticles as nano-adsorbents: A possibleway to reduce arsenic phytotoxicity in Indian mustard plant(Brassica juncea L.). J.Plant Growth Regulator, 37(2), 612-624. (IF-4.16)
    6. Chandana Pandey, Rehna Augustine, Medha Panthri, Ismat Zia, Naveen C. Bisht, and Meetu Gupta. (2017) Arsenic affects the production of glucosinolate, thiol and phytochemical compounds: A comparison of two Brassica cultivars. Plant Physiology and Biochemistry 111: 144-154.                                                                 [IF-4.27]
    7. Seema Sahay and Meetu Gupta (2017) "An update on nitric oxide and its benign role in plant responses under metal stress." Nitric Oxide, 67, 39-52.[IF-4.36]
    8. Meetu Gupta and Shikha Gupta (2017) "An Overview of Selenium Uptake, Metabolism, and Toxicity in Plants." Frontiers in Plant Science, 7.                             [IF-4.40]
    9. Chandana Pandey, Ehsanullah Khan, Medha Panthri, Rudra Deo Tripathi, Meetu Gupta (2016) Impact of silicon on Indian mustard (Brassica juncea L.) root traits by regulating growth parameters, cellular antioxidants and stress modulators under arsenic stress. Pl. Physiol. Biochem. 104, 216-225.                                                                   [IF-4.27]
    10. Chandana Pandey, Badmi Raghuram, Alok Krishna Sinha and Meetu Gupta (2015) miRNA plays a role in the antagonistic effect of selenium on arsenic stress in rice seedlings. Metallomics , 7, 857-866. [IF: 4.27]
    11. Mohd. Anwar Ahmad and  Meetu Gupta (2013) Exposure of Brassica juncea (L.) to arsenic species in hydroponic medium: comparative analysis in accumulation and biochemical and transcriptional alterations. Environ. Sci. Pollu. Res. 20(11), 8141-8150. [IF: 4.01]

    (Journals Impact factor 2-4, as corresponding author)

    1. Afsana Praveen, Ashutosh Pandey and Meetu Gupta (2020) Protective role of nitric oxide on nitrogen thiol metabolism and amino acids profiling during arsenic exposure in Oryza sativa L. Ecotoxicology, 29(7), 825-836. [IF: 2.32]
    2. Afsana Parveen, Chandana Pandey, Ehasanullah Khan, Medha Panthri and Meetu Gupta (2020) Silicon-mediated genotoxic alterations in Brassica juncea under arsenic stress: A comparative study of biochemical and molecular markers. Pedosphere, 30(4), 517-527. [IF: 3.73]
    3. Seema Sahay, Eulogio De La Cruz Torres, Luis Robledo-Arratia, Meetu Gupta (2020) Photosynthetic activity and RAPD profile of polyethylene glycol treated B.juncea L. under nitric oxide and abscisic acid application. Journal of Biotechnology, 313, 29-38. [IF: 3.16]
    4. Shikha Gupta and Meetu Gupta (2015) Alleviation of selenium toxicity in Brassica juncea L.: salicylic acid mediated modulation in toxicity indicators, stress modulators, and sulphur related gene transcripts. Protoplasma.253, 1515-1528.                                                                                                    [IF 2.75]
    5. Rashmi Gaur, Sabhyata Bhatia and Meetu Gupta (2014). Generation of expressed sequence tags under cadmium stress for gene discovery and development of molecular markers in chickpea. Protoplasma 251, 955-972. [IF: 2.75)]    
    6. Rao K.P., Vani G., Kumar K., Wankhede D.P., Misra M., Gupta M. and Sinha A.K. (2011). Arsenic stress activates MAP kinase in rice roots and leaves. Arch. Biochem. Biophy. 506, 73-82. [IF: 3.1]
    7. Gupta Meetu and Sarin N.B. (2009) Heavy metal induced DNA changes in aquatic macrophytes: RAPD analysis and identification of SCAR marker. J. Env. Sci. Vol. 21 (5), 686-690. [IF: 2.20]

    (Other Publications)

     

    1.  JA Mazumder, E Khan, M Perwez, M Gupta, S Kumar, K Raza, M Sardar (2020)  Exposure of biosynthesized nanoscale ZnO to Brassica juncea crop plant:Morphological, biochemical and molecular aspects. Scientific Reports, 10(1), 1-13. [IF: 4.37]
    2. Thoma, I, Loeffler, C, Sinha, A.K., Gupta, M.,  Krischke, M.,  Steffan, B., Roitsch, T. and Mueller, M.J. (2003) Cyclopentenone isoprostanes induced by reactive oxygen species trigger defense gene activation and phytoalexin accumulation in plants. The Plant Journal, 34, 363-375. (Cover article). [IF: 6.14]
    3. Ranade SA, Verma, A, Meetu Gupta and N. Kumar (2002) RAPD profile- based distinction between Kapoori and Bangla types of Betel vine varieties. Biologia Plantarum 45(4) 523-527. [IF: 1.34]
    4. Gupta Meetu, Kumar A, Yunus, M. (2000) Effect of fly-ash on metal composition and physiological responses in Leucaena leucocephala (Lamk.) de. wit. Environ. Monitor. Assess., 61, 399-406. [IF: 2.51]
    5. Gupta Meetu (1999) Effect of lead and mercury on changes in protein profile in the aquatic macrophytes Hydrilla verticillata (l.f.) Royle and Vallisneria spiralis L. J. Environ. Sci. Health , 34(5), 1093-1104. [IF: 1.64]
    6. Gupta Meetu, Tripathi R.D., Rai U.N. & Haq, W. (1999) Lead induced synthesis of metal binding peptides (phytochelatins) in submerged macrophyte Vallisneria spiralis L: Physiol. Mol. Biol. Plants, 5, 173-180. [IF: 2.39]
    7.  Gupta Meetu & Chandra P (1998) Mercury accumulation and physiological changes in rooted submerged plant Vallisneria spiralis L. Environ. Pollution, 103 (2-3) 327-332. [IF: 8.07]
    8. *Gupta Meetu, Tripathi, R.D., Rai,U.N. & Chandra P. (1998) Role of glutathione and phytochelatin in Hydrilla verticillata (l.f.) Royle and Vallisneria spiralis L. under mercury stress. Chemosphere, 37(4): 785-800. [IF: 7.08]
    9. Rai, U.N., Gupta  Meetu, Tripathi, R.D. & Chandra P. (1998) Cadmium regulated nitrate reductase activity in Hydrilla verticillata (l.f.) Royle. Water Air and Soil Pollution 106: 171-177. [IF: 2.63]
    10. Tripathi, R.D. Rai, U.N., Gupta Meetu & Chandra, P. (1996) Induction of phytochelatin in Hydrilla verticillata (l.f.)  Royle under cadmium stress. Bull. Environ. Contam. Toxicol. 56: 505-512. [IF: 2.15]
    11. Gupta Meetu & Chandra P. (1996) Bioaccumulation and physiological changes in Hydrilla verticillata (l.f.) Royle in response to mercury. Bull. Environ. Contam. Toxicol. 56 : 319-326. [IF: 2.15]
    12. Tripathi, R.D., Rai, U.N,  Gupta  Meetu & Chandra P. (1995) Cadmium transport in submerged macrophyte Ceratophyllum demersum L. in presence of various metabolic inhibitors and calcium channel blockers. Chemosphere. 31 (7): 3783-3791.                                                                                           [IF: 7.08]
    13. *Gupta Meetu, Rai U.N., Tripathi R.D. & Chandra P. (1995) Lead induced changes in glutathione and phytochelatin in Hydrilla verticillata (l.f.) Royle. Chemosphere 30 (10): 2011-2020.[IF: 7.08]
    14. Rai, U.N., Tripathi, R.D., Gupta Meetu & Chandra P. (1995) Induction of phytochelatin under cadmium stress in water lettuce (Pistia stratiotes) L. J. Environ. Sci. Health. A 30(9): 2007-2026. [IF: 2.10]
    15. Gupta Meetu & Chandra P. (1994) Lead accumulation and  toxicity in Vallisneria spiralis and Hydrilla verticillata (l.f.)  Royle. J.Environ. Sci. Health. A 29(3): 503-516. [IF: 2.10]

     

    (Journals Impact Factor >1)

    1. Meetu Gupta and Chandana Pandey (2013) c-DNA RAPD analysis in Oryza sativa and Brassica juncea under arsenic stress. Int. J. Adv. Res. 1(6), 489-492. [IF: 1.67].

     

    (Journals Impact factor < 1, UGC listed )

    1. Praveen, Afsana, Chandana Pandey, Ehasanullah Khan, and Meetu Gupta (2017) "Selenium enriched Garden cress (Lepidium sativum L.): Role of antioxidants and stress markers." Russian Agricultural Sciences 43, no. 2: 134-137.
    2. Afsana Praveen, Ehsanullah Khan, Chandana Pandey, Medha Panthri, Meetu Gupta (2015) Silicon mediates genotoxic alterations in Brassica juncea roots under arsenic stress. J. Agro. Nat. Res. Mang. 2(3), 203-204.
    3. Meetu Gupta, Mohd. Anwar Ahmad and Chandana Pandey (2015) Biochemical and molecular analysis in Indian mustard variety under arsenate stress. Pl. Arch. 15(1), 479-487.
    4. Meetu Gupta and Chandana Pandey (2013) Assessment of genotoxic effect of arsenic and selenium in Indian mustard (Brassica juncea L.) by using RAPD analysis. Pl. Arch. Vol. 13 No. 2, 999-1002
    5. Shikha Gupta and Meetu Gupta (2013) Indian mustard varieties (Brassica juncea) respond differently under selenium stress. Intern. J. Environ. Res. Develop. 3: 70-73.
    6. Kumar M., Gupta Meetu., Srivastava D., Prasad M., Prasad U.S. and Sarin N.B. (2006) Genetic relatedness among Indian litchi accessions (Litchi chinensis Sonn.) by RAPD markers. Int. J. Agricul. Sci. 1 (4), 390-400. [IF: 0.67]